SB-218795
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Larger quantity required? Request bulk
An NK3 receptor antagonist (Ki = 0.013 µM), selective for NK3 over NK1 and NK2 receptors (Kis =... more
Product information "SB-218795"
An NK3 receptor antagonist (Ki = 0.013 µM), selective for NK3 over NK1 and NK2 receptors (Kis = >100 and 1.221 µM, respectively), inhibits senktide-induced contractions in isolated rabbit iris sphincter muscle preparations (Kb = 43 nM), inhibits substance P-induced contraction of longitudinal and circular smooth muscles isolated from rabbit duodenum, jejunum, or ileum at 1 µM. Formulation: A solid. InChI: InChI=1S/C25H20N2O3/c1-30-25(29)23(18-12-6-3-7-13-18)27-24(28)20-16-22(17-10-4-2-5-11-17)26-21-15-9-8-14-19(20)21/h2-16,23H,1H3,(H,27,28)/t23-/m1/s1. InChIKey: IUMQXQJZIHWLIN-HSZRJFAPSA-N. SMILES: O=C(C1=CC(C2=CC=CC=C2)=NC3=C1C=CC=C3)N[C@@H](C(OC)=O)C4=CC=CC=C4
| Keywords: | aR-[[(2-phenyl-4-quinolinyl)carbonyl]amino]-benzeneacetic acid, methyl ester |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 42373 |
Properties
| Application: | NK3 receptor (TACR3) antagonist |
| Immunogen: | 396.44 |
| MW: | 396.44 D |
| Formula: | C25H20N2O3 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 174635-53-1| Matching products |
| KEGG ID : | K04224 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319 |
| P Phrases: | P264, P270, P280, P301+310, P302+352, P305+351+338, P321, P330, P332+313, P337+313, P362+364, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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