Ruxolitinib phosphate
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Ruxolitinib phosphate (INCB018424)(INCB018424 phosphate) is the first potent,... more
Product information "Ruxolitinib phosphate"
Description: Ruxolitinib phosphate (INCB018424)(INCB018424 phosphate) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Target: Autophagy, Mitophagy, JAK. Smiles: OP(O)(O)=O.N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12. References: Quintas-Cardama A, et al. Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms. Blood, 2010, 115(15), 3109-3117.
| Keywords: | INCB018424, INC 424 phosphate, INC424, INCB018424 phosphate, Ruxolitinib (INCB-18424) phosphate |
| Supplier: | TargetMol |
| Supplier-Nr: | T3043 |
Properties
| Application: | Targets Janus kinase 1 [EC:2.7.10.2] (JAK1) |
| MW: | 404.36 D |
| Formula: | C17H21N6O4P |
Database Information
| CAS : | 1092939-17-7| Matching products |
| KEGG ID : | K04447 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H361, H373 |
| P Phrases: | P201, P202, P260, P264, P270, P280, P314, P321, P330, P301+P310, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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