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Ruxolitinib . phosphate salt
Item number: AG-CR1-3645-M100
White to off-white solid. Soluble in DMSO (>100mg/ml) and water (8mg/ml). Slightly soluble in 100% ethanol. Water-soluble phosphate salt of Ruxolitinib, Antineoplastic, anti-inflammatory and immunomodulating agent, Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and...
| Keywords: | INCB018424, INC 424 |
| Application: | JAK1?/?JAK2 inhibitor |
| CAS | 1092939-17-7 |
| MW: | 404,4 D |
From 50.00€
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Ruxolitinib (phosphate)
Item number: Cay23215-10
Ruxolitinib is a potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5 nM, respectively, and is relatively less selective for JAK3 (IC50 = 322 nM). It blocks interleukin-6 (IL-6) signaling (IC50 = 281 nM) and proliferation of JAK2V617F+ Ba/F3 cells (IC50 = 127 nM). In primary cultures,...
| Keywords: | INC 424 (phosphate), INCB 018424 (phosphate),... |
| Application: | Janus kinase inhibitor |
| CAS | 1092939-17-7 |
| MW: | 404.4 D |
From 43.00€
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Ruxolitinib, Phosphate Salt (INCB018424, INCB18424,...
Item number: LC-R-6688_100mg
Soluble in DMSO at 200 mg/mL, very poorly soluble in ethanol, soluble in water at 8 mg/mL with warming, buffers, serum, or other additives may increase or decrease the aqueous solubility
| Keywords: | INC 424 (phosphate), INCB 018424 (phosphate),... |
| Application: | Janus kinase inhibitor |
| CAS | 1092939-17-7 |
| MW: | 404,36 D |
From 204.00€
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