Rg3039
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Rg3039 (PF-06687859) is a potent DcpS inhibitor. DcpS is a therapeutic target for... more
Product information "Rg3039"
Description: Rg3039 (PF-06687859) is a potent DcpS inhibitor. DcpS is a therapeutic target for spinal muscular atrophy. Spinal muscular atrophy (SMA) is caused by deletion or mutation of both copies of the SMN1 gene which produces an essential protein known as SMN. RG3039 improves motor function in SMA mice. RG3039 also showed activity to improve survival, function and motor unit pathologies in two SMA mouse models. Target: Others. Smiles: Nc1nc(N)c2c(OCC3CCN(Cc4c(Cl)cccc4Cl)CC3)cccc2n1. References: Rocky G. Gogliotti, et al. Hum Mol Genet. 2013 Oct 15, 22(20): 4084-4101.
| Keywords: | PF-06687859 |
| Supplier: | TargetMol |
| Supplier-Nr: | T3336 |
Properties
| Application: | DcpS (m7GpppX diphosphatase) inhibitor |
| MW: | 432.35 D |
| Formula: | C21H23Cl2N5O |
Database Information
| CAS : | 1005504-62-0| Matching products |
| KEGG ID : | K12584 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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