RG-14620

RG-14620
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10010310-5 5 mg -

6 - 10 business days*

58.00€
Cay10010310-10 10 mg -

6 - 10 business days*

109.00€
Cay10010310-50 50 mg -

6 - 10 business days*

460.00€
 
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases... more
Product information "RG-14620"
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation. RG-14620 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 3 µM in HT-22 cells. Formal Name: alpha-[(3,5-dichlorophenyl)methylene]-3-pyridineacetonitrile. CAS Number: 136831-49-7. Molecular Formula: C14H8Cl2N2. Formula Weight: 275.1. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 1 mg/ml. lambdamax: 206, 309 nm. SMILES: ClC1=CC(/C=C(C#N)/C2=CN=CC=C2)=CC(Cl)=C1. InChi Code: InChI=1S/C14H8Cl2N2/c15-13-5-10(6-14(16)7-13)4-12(8-17)11-2-1-3-18-9-11/h1-7,9H/b12-4+. InChi Key: TYXIVBJQPBWBHO-UUILKARUSA-N.
Keywords: alpha-[(3,5-dichlorophenyl)methylene]-3-pyridineacetonitrile
Supplier: Cayman Chemical
Supplier-Nr: 10010310

Properties

Application: EGF receptor kinase inhibitor
MW: 275.1 D
Formula: C14H8Cl2N2
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 136831-49-7| Find alternatives
KEGG ID : K04361 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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