Pulsatilla Saponin D

Pulsatilla saponin D is an oleanane-type saponin that has been found in P. koreana and has anticancer activity. It is cytotoxic to A549, SKOV3, SK-MEL-2, and HCT15 cells (EC50s = 11.25, 13.17, 3.04, and 11.86 µM, respectively). Pulsatilla saponin D (6 mg/kg per day) reduces tumor volume in a murine Lewis lung carcinoma model.Formal Name: (3beta,4alpha)-3-[[O-6-deoxy-alpha-L-mannopyranosyl-(1->2)-O-[beta-D-glucopyranosyl-(1->4)]-alpha-L-arabinopyranosyl]oxy]-23-hydroxy-olean-12-en-28-oic acid. CAS Number: 68027-15-6. Synonyms: Hederagenin 3-O-alpha-L-rhamnopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->4)]-alpha-L-arabinopyranoside, Hederacolchiside A, Pulchinenoside B3. Molecular Formula: C47H76O17. Formula Weight: 913.1. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 15 mg/ml, DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml, DMSO: 5 mg/ml, Ethanol: 10 mg/ml. SMILES: CC1(C)CC[C@@]2(C(O)=O)[C@@](C3=CC[C@@]([C@](CC[C@H](O[C@H]4[C@H](O[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@@H](O)[C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)CO4)[C@]7(CO)C)(C)[C@@]7([H])CC8)([H])[C@]8(C)[C@]3(C)CC2)([H])C1. InChi Code: InChI=1S/C47H76O17/c1-22-30(50)33(53)35(55)38(60-22)64-37-32(52)26(62-39-36(56)34(54)31(51)25(19-48)61-39)20-59-40(37)63-29-11-12-43(4)27(44(29,5)21-49)10-13-46(7)28(43)9-8-23-24-18-42(2,3)14-16-47(24,41(57)58)17-15-45(23,46)6/h8,22,24-40,48-56H,9-21H2,1-7H3,(H,57,58)/t22-,24-,25+,26-,27+,28+,29-,30-,31+,32-,33+,34-,35+,36+,37+,38-,39-,40-,43-,44-,45+,46+,47-/m0/s1. InChi Key: SOLICHUQXFAOEP-YDIXZRNLSA-N. Origin: Plant/Pulsatilla chinensis.