Description: Pulsatilla saponin D (Hederacolchiside A) has exhibited potential beneficial effects as a chemopreventive agent for critical health conditions including cancer, and it inhibits cell growth via cell cycle arrest and apoptosis in various cancer cell types. Target: Apoptosis, Others. Smiles:...

Pulsatilla saponin D is an oleanane-type saponin that has been found in P. koreana and has anticancer activity. It is cytotoxic to A549, SKOV3, SK-MEL-2, and HCT15 cells (EC50s = 11.25, 13.17, 3.04, and 11.86 µM, respectively). Pulsatilla saponin D (6 mg/kg per day) reduces tumor volume in a murine Lewis lung...