Prodigiosin

Prodigiosin is a natural red bacterial pigment that has antibiotic, antitumor, and immunosuppressant properties. It blocks T cell proliferation at a concentration of 30 ng/ml, by interfering with IL-2 receptor expression. Prodigiosin induces apoptosis in cancer cells by diverse mechanisms and rescues deficient p53 signaling. Prodigiosin derivatives can uncouple vacuolar H+-ATPase and inhibit osteoclast function. Prodigiosin is cytolytic against the red tide dinoflagellate Cochlodinium at very low concentrations (1 ppb), suggesting an application in controlling algal blooms.Formal Name: 4-methoxy-5-[(5-methyl-4-pentyl-2H-pyrrol-2-ylidene)methyl]-2,2'-bi-1H-pyrrole. CAS Number: 82-89-3. Synonyms: BRN 4526727, NSC 47147. Molecular Formula: C20H25N3O. Formula Weight: 323.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: Soluble, Ethanol: Soluble, Methanol: Soluble. SMILES: CC1=N/C(C=C1CCCCC)=C/C(N2)=C(OC)C=C2C3=CC=CN3. InChi Code: InChI=1S/C20H25N3O/c1-4-5-6-8-15-11-16(22-14(15)2)12-19-20(24-3)13-18(23-19)17-9-7-10-21-17/h7,9-13,21,23H,4-6,8H2,1-3H3/b16-12+. InChi Key: SZXDNGVQRDTJSD-FOWTUZBSSA-N.