Red-pigmented antibiotic, antimalarial, immunosuppressive, apoptosis inducer, cytotoxic. Induces phosphorylation of p38-MAPK, antimetastatic. Tumor invasion inhibitor, induces p21WAF1/CIP1 expression, anticancer compound, gp91(phox) and iNOS expression inhibitor, mTORC1 and mTORC2 complexe inhibitor, down-regulates...

Prodigiosin is a natural red bacterial pigment that has antibiotic, antitumor, and immunosuppressant properties. It blocks T cell proliferation at a concentration of 30 ng/ml, by interfering with IL-2 receptor expression. Prodigiosin induces apoptosis in cancer cells by diverse mechanisms and rescues deficient p53...

Description: Prodigiosin is a secondary metabolite of Symbiotic bacteria. It also has anti-fungal and anti-cancer activity. Target: Antifungal. Smiles: CCCCCC1=CC(=Cc2[nH]c(cc2OC)-c2ccc[nH]2)N=C1C , w:8.8,c:23,t:5, . References: Woodhams DC, et al. Prodigiosin, Violacein, and Volatile Organic Compounds Produced by...

Prodigiosin is an intensely red pyrrole pigment produced by several bacteria, most notably, Serratia marcescens. Prodigiosin has a broad biological profile with activity against fungi, tumor cell lines and malaria. It was shown to be an immunosuppressant in 2007. The mode of action of prodigiosin has recently...