Ponatinib Hydrochloride

Item number	Size	Delivery time	Price
TGM-T2372L-10mg	10 mg	7 - 10 business days*	40.00€
TGM-T2372L-25mg	25 mg	7 - 10 business days*	72.00€
TGM-T2372L-50mg	50 mg	7 - 10 business days*	112.00€
TGM-T2372L-100mg	100 mg	7 - 10 business days*	172.00€
TGM-T2372L-200mg	200 mg	7 - 10 business days*	253.00€
TGM-T2372L-500mg	500 mg	7 - 10 business days*	433.00€

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Description: Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib.... more

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Product information "Ponatinib Hydrochloride"

Description: Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRalpha, VEGFR2, FGFR1, and Src, respectively. Target: VEGFR, FGFR, PDGFR, Src. Smiles: Cl.CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cnc4cccnn34)cc2C(F)(F)F)CC1. References: O'Hare T, et al. AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance. Cancer Cell, 2009, 16(5), 401-412.

Keywords:	AP-24534, AP24534 Hydrochloride, AP24534, Ponatinib hydrochloride, AP 24534, AP-24534 Hydrochloride
Supplier:	TargetMol
Supplier-Nr:	T2372L

Properties

Application:	Targets abelson tyrosine-protein kinase 1 [EC:2.7.10.2] (ABL1)
MW:	569.02 D
Formula:	C29H28ClF3N6O

Database Information

CAS :	1114544-31-8\| Matching products
KEGG ID :	K06619 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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