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Ponatinib Hydrochloride
Item number: TGM-T2372L-100mg
Description: Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRalpha, VEGFR2, FGFR1, and Src, respectively. Target: VEGFR, FGFR, PDGFR, Src. Smiles:...
| Keywords: | AP-24534, AP24534 Hydrochloride, AP24534, Ponatinib hydrochloride, AP 24534, AP-24534 Hydrochloride |
| CAS | 1114544-31-8 |
| MW: | 569.02 D |
From 38.00€
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Ponatinib (hydrochloride)
Item number: Cay35778-50
Ponatinib is an orally bioavailable Bcr-Abl tyrosine kinase inhibitor (IC50 = 0.37 nM). It inhibits the tyrosine kinase inhibitor-resistant mutant Bcr-AblT315I (IC50 = 2 nM), as well as Bcr-AblQ252H, Bcr-AblY253F, Bcr-AblM351T, and Bcr-AblH396P mutants (IC50s = 0.44, 0.3, 0.3, and 0.34 nM, respectively). It is...
| Keywords: | AP 24534,... |
| Application: | Native / mutant Bcr-Abl inhibitor |
| CAS | 1114544-31-8 |
| MW: | 569 D |
From 62.00€
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