PFM01
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
PFM01 is an inhibitor of the endonuclease activity of the double-strand break repair protein... more
Product information "PFM01"
PFM01 is an inhibitor of the endonuclease activity of the double-strand break repair protein Mre11. It decreases the number of chromosomal breaks in 1BR3 fibroblasts induced by knockdown of BRCA2. PFM01 (50 µM) reduces homologous recombination-mediated DNA repair in DR-GFP U2OS cells and enhances DNA repair mediated by non-homologous end-joining (NHEJ) in H1299 dA3 cells.Formal Name: 5Z-[(4-hydroxyphenyl)methylene]-3-(2-methylpropyl)-2-thioxo-4-thiazolidinone. CAS Number: 1558598-41-6. Molecular Formula: C14H15NO2S2. Formula Weight: 293.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 29.3 mg/ml. SMILES: OC(C=C1)=CC=C1/C=C2SC(N(CC(C)C)C\2=O)=S. InChi Code: InChI=1S/C14H15NO2S2/c1-9(2)8-15-13(17)12(19-14(15)18)7-10-3-5-11(16)6-4-10/h3-7,9,16H,8H2,1-2H3/b12-7-. InChi Key: GPURHDUTZUYAFI-GHXNOFRVSA-N.
| Keywords: | 5Z-[(4-hydroxyphenyl)methylene]-3-(2-methylpropyl)-2-thioxo-4-thiazolidinone |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 36574 |
Properties
| Application: | Mre11 endonuclease activity inhibitor |
| MW: | 293.4 D |
| Formula: | C14H15NO2S2 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 1558598-41-6| Matching products |
| KEGG ID : | K10865 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319 |
| P Phrases: | P264, P280, P321, P302+P352, P305+P351+P338, P332+P313, P337+P313, P362+P364 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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