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Item number: Cay36574-10

PFM01 is an inhibitor of the endonuclease activity of the double-strand break repair protein Mre11. It decreases the number of chromosomal breaks in 1BR3 fibroblasts induced by knockdown of BRCA2. PFM01 (50 µM) reduces homologous recombination-mediated DNA repair in DR-GFP U2OS cells and enhances DNA repair mediated...

Keywords:	5Z-[(4-hydroxyphenyl)methylene]-3-(2-methylpropyl)-2-thioxo-4-thiazolidinone
Application:	Mre11 endonuclease activity inhibitor
CAS	1558598-41-6
MW:	293.4 D

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