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Item number: TGM-T8880-100mg

Description: PFM01 is an inhibitor of MRE11 endonuclease. PFM01 can regulate double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) versus homologous recombination (HR). Target: Others. Smiles: CC(C)CN1C(=S)S\C(=C/c2ccc(O)cc2)C1=O. References: Shibata A, et, al. DNA double-strand break repair pathway...

Application:	Mre11 endonuclease activity inhibitor
CAS	1558598-41-6
MW:	293.4 D

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PFM01

Item number: Cay36574-10

PFM01 is an inhibitor of the endonuclease activity of the double-strand break repair protein Mre11. It decreases the number of chromosomal breaks in 1BR3 fibroblasts induced by knockdown of BRCA2. PFM01 (50 µM) reduces homologous recombination-mediated DNA repair in DR-GFP U2OS cells and enhances DNA repair mediated...

Keywords:	5Z-[(4-hydroxyphenyl)methylene]-3-(2-methylpropyl)-2-thioxo-4-thiazolidinone
Application:	Mre11 endonuclease activity inhibitor
CAS	1558598-41-6
MW:	293.4 D

From 66.00€ *

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