PFI-2 hydrochloride
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and... more
Product information "PFI-2 hydrochloride"
Description: PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM), 500 fold active than (S)-PFI-2. Target: Histone Methyltransferase. Smiles: Cl.Fc1cc(cc2CCNCc12)S(=O)(=O)N[C@H](Cc1cccc(c1)C(F)(F)F)C(=O)N1CCCC1. References: Barsyte-Lovejoy D, et al. (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells. Proc Natl Acad Sci U S A. 2014 Sep 2,111(35):12853-8.
| Keywords: | (R)-PFI-2 hydrochloride, PFI-2 HCl |
| Supplier: | TargetMol |
| Supplier-Nr: | T4583 |
Properties
| Application: | Cell-permeable SET7/9 inhibitor |
| MW: | 535.98 D |
| Formula: | C23H26ClF4N3O3S |
Database Information
| CAS : | 1627607-87-7| Matching products |
| KEGG ID : | K11431 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P301+310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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