PF-3882845
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| TGM-T16502-25mg | 25 mg |
7 - 10 business days* |
470.00€
|
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| TGM-T16502-50mg | 50 mg |
7 - 10 business days* |
786.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: PF-3882845 also binds to the progesterone receptor (the binding IC50: 310 nM).... more
Product information "PF-3882845"
Description: PF-3882845 also binds to the progesterone receptor (the binding IC50: 310 nM). PF-3882845 is a remarkably high affinity selective and orally efficacious mineralocorticoid receptor (MR binding IC50=2.7 nM) antagonist for hypertension and nephropathy. Target: Others. Smiles: ClC=1C=C(N2[C@H]([C@@]3(C(=N2)C=4C(CC3)=CC(C(O)=O)=CC4)[H])C5CCCC5)C=CC1C#N. References: Meyers MJ, et al. Discovery of (3S,3aR)-2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic acid (PF-3882845), an orally efficacious mineralocorticoid receptor (MR) antagonist for hypertension and nephropathy. J Med Chem. 2010 Aug 26,53(16):5979-6002.
| Supplier: | TargetMol |
| Supplier-Nr: | T16502 |
Properties
| MW: | 419.9 D |
| Formula: | C24H22ClN3O2 |
Database Information
| CAS : | 1023650-66-9| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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