PF-06454589

Item number	Size	Manual	Delivery time	Price
Cay42957-5	5 mg	-	6 - 10 business days*	142.00€
Cay42957-10	10 mg	-	6 - 10 business days*	227.00€
Cay42957-25	25 mg	-	6 - 10 business days*	423.00€
Cay42957-50	50 mg	-	6 - 10 business days*	635.00€

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PF-06454589 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 = 12 nM for the... more

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Product information "PF-06454589"

PF-06454589 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 = 12 nM for the wild-type enzyme). It also inhibits LRRK2 containing a glycine-to-serine substitution at position 2019 (LRRK2G2019S, IC50 = 36 nM).. Solulibility: DMSO: Slightly soluble: 0.1-1 mg/ml: .

Keywords:	5-(1-methyl-1H-pyrazol-4-yl)-4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidine
Supplier:	Cayman Chemical
Supplier-Nr:	42957

Properties

Application:	LRRK2 inhibitor
MW:	284.32 D
Formula:	C14H16N6O
Purity:	>95%
Format:	Solid

Database Information

CAS :	1527473-30-8\| Matching products
KEGG ID :	K08844 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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