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PF-06454589
PF-06454589

Item number: Cay42957-10

PF-06454589 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 = 12 nM for the wild-type enzyme). It also inhibits LRRK2 containing a glycine-to-serine substitution at position 2019 (LRRK2G2019S, IC50 = 36 nM).. Solulibility: DMSO: Slightly soluble: 0.1-1 mg/ml: .
Keywords: 5-(1-methyl-1H-pyrazol-4-yl)-4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidine
Application: LRRK2 inhibitor
CAS 1527473-30-8
MW: 284.32 D
From 142.00€ *
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PF-06454589
PF-06454589

Item number: TGM-T7729-100mg

Description: PF-06454589 is a potent inhibitor of LRRK2. Target: LRRK2. Smiles: Cn1cc(cn1)-c1c[nH]c2ncnc(N3CCOCC3)c12
CAS 1527473-30-8
MW: 284.32 D
From 30.00€ *
Review