PF-06447475
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
PF-06447475 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 = 3 nM), an enzyme... more
Product information "PF-06447475"
PF-06447475 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 = 3 nM), an enzyme genetically linked to Parkinson's disease that interacts with parkin, a ligase whose loss of function leads to dopaminergic cell death. PF-06447475 has been shown to attenuate alpha-synuclein-induced dopaminergic neurodegeneration and neuroinflammation in G2019S-LRRK2-expressing rats.
| Keywords: | 3-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-benzonitrile |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 18375 |
Properties
| Application: | LRRK2 inhibitor |
| MW: | 305.3 D |
| Formula: | C17H15N5O |
| Purity: | >98% |
| Format: | Crystalline Solid |
Database Information
| CAS : | 1527473-33-1| Matching products |
| KEGG ID : | K08844 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301 |
| P Phrases: | P264, P270, P301+310, P321, P330, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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