PF-05221304

Item number	Size	Delivery time	Price
TGM-T9209-1mg	1 mg	7 - 10 business days*	86.00€
TGM-T9209-5mg	5 mg	7 - 10 business days*	175.00€
TGM-T9209-10mg	10 mg	7 - 10 business days*	264.00€
TGM-T9209-1mL	1 ml	7 - 10 business days*	266.00€
TGM-T9209-25mg	25 mg	7 - 10 business days*	458.00€
TGM-T9209-50mg	50 mg	7 - 10 business days*	597.00€
TGM-T9209-100mg	100 mg	7 - 10 business days*	870.00€
TGM-T9209-200mg	200 mg	7 - 10 business days*	1,170.00€

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Description: PF-05221304 (NSC-170984) is an orally active, liver-targeted inhibitor of acetyl-CoA... more

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Product information "PF-05221304"

Description: PF-05221304 (NSC-170984) is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis. Target: Acetyl-CoA Carboxylase. Smiles: O=C1CC2(CC3=C1N(C(C)C)N=C3)CCN(C(=O)C=4C=C(N=C(OC)C4)C5=CC=C(C(O)=O)C=C5)CC2. References: Ross T T , Crowley C , Kelly K L , et al. Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems[J]. Cellular and Molecular Gastroenterology and Hepatology, 2020, 10(4).

Keywords:	Clesacostat, R 6238,, STAT5 Inhibitor III, NSC 170984
Supplier:	TargetMol
Supplier-Nr:	T9209

Properties

Application:	Targets acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15] (ACACA)
MW:	502.56 D
Formula:	C28H30N4O5

Database Information

CAS :	1370448-25-1\| Matching products
KEGG ID :	K01946 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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