Perindopril

Perindopril is an orally active angiotensin converting enzyme (ACE) inhibitor that effectively lowers blood pressure. It is a prodrug that is metabolized to perindoprilat (Cay-17574), a specific, competitive inhibitor of ACE (IC50 = 1.5-3.2 nM in vitro).Formal Name: (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid. CAS Number: 82834-16-0. Molecular Formula: C19H32N2O5. Formula Weight: 368.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Ethanol: 25 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: [H][C@]12[C@](N(C([C@H](C)N[C@@H](CCC)C(OCC)=O)=O)[C@H](C(O)=O)C2)([H])CCCC1. InChi Code: InChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13-,14-,15-,16-/m0/s1. InChi Key: IPVQLZZIHOAWMC-QXKUPLGCSA-N.