PDGFRalpha kinase inhibitor 1

PDGFRalpha kinase inhibitor 1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T12396-2mg 2 mg

7 - 10 business days*

397.00€
 
Description: PDGFRalpha kinase inhibitor 1 is a highly selective inhibitor of type II PDGFRalpha... more
Product information "PDGFRalpha kinase inhibitor 1"
Description: PDGFRalpha kinase inhibitor 1 is a highly selective inhibitor of type II PDGFRalpha kinase (PDGFRalpha and PDGFRbeta) with IC50 values of 132 nM and 6115 nM, respectively. Target: PDGFR. Smiles: CN(C)CCN(Cc1ccc(cc1)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1)C(=O)c1cccnc1. References: Wang Q, et al. Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRalpha kinase inhibitor for PDGFRalpha driving chronic eosinophilic leukemia. Eur J Med Chem. 2018 Apr 25,150:366-384.
Supplier: TargetMol
Supplier-Nr: T12396

Properties

Application: PDGFRalpha kinase inhibitor
MW: 586.69 D
Formula: C34H34N8O2

Database Information

CAS : 2209053-93-8| Matching products
KEGG ID : K04363 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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