239 products were found matching "K04363"!

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Anti-PDGFR alpha / PDGFRA, clone AAOE-16
Anti-PDGFR alpha / PDGFRA, clone AAOE-16

Item number: NSJ-RQ5478

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The PDGFRA gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a...
Keywords: Anti-CD140a, Anti-PDGFR2, Anti-PDGFRA, Anti-PDGFR-2, Anti-PDGFR-alpha, EC=2.7.10.1, Anti-PDGF-R-alpha, Anti-CD140a...
Application: WB
Host: Rabbit
Species reactivity: human
755.00€ *
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Rat PDGFRa (Platelet Derived Growth Factor Receptor Alpha) ELISA Kit
Rat PDGFRa (Platelet Derived Growth Factor Receptor...

Item number: ELK-ELK5831.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat PDGFRa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat PDGFRa. Next,...
Keywords: CD140a, Pdgfra, PDGFR-alpha, EC=2.7.10.1, PDGF-R-alpha, CD140 antigen-like family member A, Platelet-derived growth factor...
Application: ELISA
Species reactivity: rat
365.00€ * From 328.50€ *
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Human PDGFRa (Platelet Derived Growth Factor Receptor Alpha) ELISA Kit
Human PDGFRa (Platelet Derived Growth Factor Receptor...

Item number: ELK-ELK2768.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PDGFRa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PDGFRa....
Keywords: CD140a, PDGFR2, PDGFRA, PDGFR-2, PDGFR-alpha, EC=2.7.10.1, PDGF-R-alpha, CD140a antigen, CD140 antigen-like family member...
Application: ELISA
Species reactivity: human
365.00€ * From 328.50€ *
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Anti-CD140a / PDGFRA (PE-Cyanine 7), clone 16A1
Anti-CD140a / PDGFRA (PE-Cyanine 7), clone 16A1

Item number: ARG43854.100

Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an...
Keywords: Anti-PDGFRA, Anti-PDGFR2, Anti-CD140a, Anti-CD140a, Anti-PDGFR-2, Anti-PDGFR-2, Anti-PDGFR-alpha, Anti-PDGFR-alpha,...
Application: FC
Host: Mouse
Species reactivity: human
696.00€ *
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Seralutinib
Seralutinib

Item number: Cay37754-25

Seralutinib is an inhibitor of PDGFR, c-Kit, and colony stimulating factor 1 receptor (CSF1R). It inhibits PDGF-BB-induced phosphorylation of ERK in PDGFRalpha-dependent H1703 human lung epithelial cells, human pulmonary arterial smooth muscle cells (HPASMCs), which express PDGFRalpha and PDGFRbeta, and human lung...
Keywords: GB002, PK 10571, N-[3-[(1S)-1-[[6-(3,4-dimethoxyphenyl)-2-pyrazinyl]amino]ethyl]phenyl]-5-methyl-3-pyridinecarboxamide
Application: PDGFR / c-Kit / CSF1R inhibitor
CAS 1619931-27-9
MW: 469.5 D
From 130.00€ *
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Lenvatinib
Lenvatinib

Item number: Cay19375-5

Lenvatinib is an inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and VEGFR3 (IC50s = 4 and 5.2 nM, respectively). It also inhibits the related kinases VEGFR1, FGFR1, PDGFRalpha, PDGFRbeta and Kit (IC50s = 22, 46, 51, 39, and 100 nM, respectively). Lenvatinib (30 mg/kg, twice per day) reduces...
Keywords: E-7080, ER-203492-00, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide
Application: VEGFR / FGFR / PDGFR inhibitor
CAS 417716-92-8
MW: 426.9 D
From 43.00€ *
Review
AG-1296
AG-1296

Item number: Cay10010592-1

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors specific for platelet-derived growth factor (PDGF) receptor kinase could help in the...
Keywords: Tyrphostin AG-1296, 6,7-dimethoxy-2-phenyl-quinoxaline
Application: PDGF receptor kinase inhibitor
CAS 146535-11-7
MW: 266.3 D
From 38.00€ *
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SU 4312
SU 4312

Item number: Cay20213-1

SU 4312 is a selective, cell-permeable inhibitor of VEGFR2 and PDGFR tyrosine kinases (IC50s = 0.8 and 19.4 µM, respectively). It demonstrates IC50 values >100 µM at EGFR, HER2, and IGF-1R. SU 4312 has been shown to inhibit VEGF-dependent angiogenesis in a zebrafish assay (IC50 = 1.8 µM) without affecting normal...
Keywords: NSC 86429, 3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one
Application: Selective, cell-permeable VEGFR2 / PDGFR inhibitor
CAS 5812-07-7
MW: 264.3 D
From 43.00€ *
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Radotinib
Radotinib

Item number: Cay19923-1

Radotinib is a selective second generation tyrosine kinase inhibitor that targets both the wild-type and mutant forms of Bcr-Abl, with an IC50 value of 30.6 nM in Ba/F3 human chronic myeloid leukemia cells expressing the wild-type form. Radotinib also inhibits platelet-derived growth factor receptors (PDGFRs) alpha...
Keywords: IY-5511,...
Application: Bcr-Abl tyrosine kinase & PDGFR inhibitor
CAS 926037-48-1
MW: 530.5 D
From 43.00€ *
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c-Kit-IN-1
c-Kit-IN-1

Item number: Cay26174-1

c-Kit-IN-1 is a dual inhibitor of c-Kit and c-MET (IC50s = 50s = 50 = 98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMF:PBS (pH 7.2) (1:5): 0.1 mg/ml, DMSO: 14 mg/ml, Ethanol: Partially soluble. lambdamax: 250 nm. SMILES:...
Keywords: N-[2,5-difluoro-4-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]phenyl]-N'-phenyl-1,1-cyclopropanedicarboxamide
Application: KIT / PDGFR inhibitor
CAS 1225278-16-9
MW: 489.5 D
From 43.00€ *
Review
Platelet Derived Growth Factor Receptor, Alpha, His Tag, human recombinant (rHuPDGFRA-His)
Platelet Derived Growth Factor Receptor, Alpha, His Tag,...

Item number: 97557.1

Human recombinant PDGFRA produced in E.coli is a single, non-glycosylated polypeptide chain containing 522 amino acids (24-524) and having a molecular mass of 58.4 kDa. The PDGFRA is fused to a 20 amino acid His-Tag at N-terminus. PDGFRa is a cell surface tyrosine kinase receptor for PDGF family members. PDGFRa...
Keywords: Platelet-derived growth factor receptor alpha polypeptide, PDGFR2, PDGF-R-alpha, CD140 antigen-like family member A,...
Application: Bioassay
Expressed in: E.coli
Origin: human
MW: 58400 D
From 94.00€ *
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Anti-CD140a / PDGF-RA, clone 16A1 (APC)
Anti-CD140a / PDGF-RA, clone 16A1 (APC)

Item number: ARG54189.50

Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an...
Keywords: Anti-CD140a, Anti-PDGFR2, Anti-PDGFRA, Anti-PDGFR-2, Anti-PDGFR-alpha, EC=2.7.10.1, Anti-PDGF-R-alpha, Anti-CD140a...
Application: FC, ICC, IF
Host: Mouse
Species reactivity: human
520.00€ *
Review
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