PD 407824
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| TGM-T16446-1mg | 1 mg |
7 - 10 business days* |
69.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity... more
Product information "PD 407824"
Description: PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity to subthreshold amounts of BMP4.PD 407824 is a potent inhibitor of the checkpoint kinases Chk1 and WEE1 (IC50s: 47 and 97 nM, respectively). Target: Chk, Wee1. Smiles: Oc1ccc2[nH]c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1. References: Palmer BD, et al. 4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione inhibitors of the checkpoint kinase WeeStructure-activity relationships for chromophore modification and phenyl ring substitution. J Med Chem. 2006 Aug 10,49(16):4896-911.
| Keywords: | PD-407824 |
| Supplier: | TargetMol |
| Supplier-Nr: | T16446 |
Properties
| Application: | Chk1 / WEE1 inhibitor |
| MW: | 328.32 D |
| Formula: | C20H12N2O3 |
Database Information
| CAS : | 622864-54-4| Matching products |
| KEGG ID : | K02216 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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