PD 318088

PD 318088
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay30265-1 1 mg -

6 - 10 business days*

61.00€
Cay30265-5 5 mg -

6 - 10 business days*

264.00€
Cay30265-10 10 mg -

6 - 10 business days*

467.00€
Cay30265-25 25 mg -

6 - 10 business days*

948.00€
 
PD 318088 is an allosteric inhibitor of MEK1 and an analog of the MEK inhibitor PD 184352... more
Product information "PD 318088"
PD 318088 is an allosteric inhibitor of MEK1 and an analog of the MEK inhibitor PD 184352 (CI-1040, Cay-11580). PD318088 binds to MEK1 concurrently with Mg-ATP and stabilizes an inactive conformation of MEK1, as well as prevents formation of tetramers and higher-order oligomers.Formal Name: 5-bromo-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide. CAS Number: 391210-00-7. Molecular Formula: C16H13BrF3IN2O4. Formula Weight: 561.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:4): 0.20 mg/ml, Ethanol: 1 mg/ml. lambdamax: 239, 284 nm. SMILES: BrC1=C(F)C(F)=C(NC2=C(F)C=C(I)C=C2)C(C(NOCC(O)CO)=O)=C1. InChi Code: InChI=1S/C16H13BrF3IN2O4/c17-10-4-9(16(26)23-27-6-8(25)5-24)15(14(20)13(10)19)22-12-2-1-7(21)3-11(12)18/h1-4,8,22,24-25H,5-6H2,(H,23,26). InChi Key: XXSSGBYXSKOLAM-UHFFFAOYSA-N.
Keywords: 5-bromo-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide
Supplier: Cayman Chemical
Supplier-Nr: 30265

Properties

Application: Allosteric MEK1 inhibitor
MW: 561.1 D
Formula: C16H13BrF3IN2O4
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 391210-00-7| Matching products
KEGG ID : K04368 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "PD 318088"
Write a review
or to review a product.
Viewed