PD 146176

PD 146176
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10010518-5 5 mg -

6 - 10 business days*

Cay10010518-10 10 mg -

6 - 10 business days*

Cay10010518-25 25 mg -

6 - 10 business days*

Cay10010518-50 50 mg -

6 - 10 business days*

PD 146176 is a potent and selective inhibitor of reticulocyte 15-lipoxygenase-1. It limits... more
Product information "PD 146176"
PD 146176 is a potent and selective inhibitor of reticulocyte 15-lipoxygenase-1. It limits hypercholesterolemia-induced atherosclerosis in New Zealand White rabbits and reduces oxidant stress-induced apoptosis in endothelial cells. PD 146176 inhibits amyloid beta protein aggregate formation without changing total levels of amyloid beta precursor protein (APP) in cells stably expressing APP. In addition, it lacks significant non-specific antioxidant properties. Formal Name: 6,11-dihydro-[1]benzothiopyrano[4,3-b]indole. CAS Number: 4079-26-9. Synonyms: NSC 168807. Molecular Formula: C15H11NS. Formula Weight: 237.3. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 10 mg/ml, DMF:PBS (pH 7.2) (1:5): 0.15 mg/ml, DMSO: 10 mg/ml, Ethanol: 2 mg/ml. SMILES: c1ccc2c(c1)SCc1c2[nH]c2ccccc12. InChi Code: InChI=1S/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2. InChi Key: ZGOOPZVQMLHPFM-UHFFFAOYSA-N.
Keywords: NSC 168807, 6,11-dihydro-[1]benzothiopyrano[4,3-b]indole
Supplier: Cayman Chemical
Supplier-Nr: 10010518


Application: 15-LO inhibitor
MW: 237.3 D
Formula: C15H11NS
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 4079-26-9| Find alternatives
KEGG ID : K00460 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Our products are for laboratory research use only: Not for administration to humans!
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