PD 117519

PD 117519 is an adenosine receptor agonist. It selectively binds to adenosine A2 receptors (IC50 = 30 µM) over A1 receptors (IC50 = 810 µM) in rat brain membranes. PD 117519 increases heart rate and decreases systolic blood pressure in normotensive dogs when administered at doses of 2 or 10 mg/kg.Formal Name: N-[(1R)-2,3-dihydro-1H-inden-1-yl]-adenosine. CAS Number: 96392-15-3. Synonyms: CI-947. Molecular Formula: C19H21N5O4. Formula Weight: 383.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 10mg/mL, DMF:PBS (pH 7.2) (1:4): 0.2mg/mL, DMSO: 5mg/mL, Ethanol: 0.1mg/mL. lambdamax: 211, 273 nm. SMILES: OC[C@H]([C@@H](O)[C@H]1O)O[C@@]1([H])N2C=NC3=C(N[C@@H]4CCC5=C4C=CC=C5)N=CN=C32. InChi Code: InChI=1S/C19H21N5O4/c25-7-13-15(26)16(27)19(28-13)24-9-22-14-17(20-8-21-18(14)24)23-12-6-5-10-3-1-2-4-11(10)12/h1-4,8-9,12-13,15-16,19,25-27H,5-7H2,(H,20,21,23)/t12-,13-,15-,16-,19-/m1/s1. InChi Key: FSKMJUWPFLDDRS-BYMDKACISA-N.