Oxatomide
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Oxatomide (Oxatomida) is a potent and orally active dual H1 histamine receptor and... more
Product information "Oxatomide"
Description: Oxatomide (Oxatomida) is a potent and orally active dual H1 histamine receptor and P2X7 receptor antagonist with antihistamine and antiallergic activity.Oxatomide can be used to block ATP-induced currents in the human P2X7 receptor with an IC50 value of 0.95 µM.Oxatomide has an inhibitory effect on ATP-induced Ca2+ inward currents with an IC50 value of 0.43 µM.Oxatomide inhibits 5-hydroxytryptamine. Oxatomide inhibits 5-hydroxytryptamine with an IC50 of 0.43 µM.Oxatomide is used in the treatment of immune system diseases and in the study of hypersensitivity reactions. Target: Calcium Channel, P2X Receptor, 5-HT Receptor, Histamine Receptor. Smiles: O=C1NC2=C(C=CC=C2)N1CCCN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=CC=C1. References: Yoshida K, et al. P2X7 receptor antagonist activity of the anti-allergic agent oxatomide. Eur J Pharmacol. 2015,767:41-51.
| Keywords: | Oxatomida |
| Supplier: | TargetMol |
| Supplier-Nr: | T19839 |
Properties
| Application: | Targets arachidonate 5-lipoxygenase [EC:1.13.11.34] (ALOX5) |
| MW: | 426.55 D |
| Formula: | C27H30N4O |
Database Information
| CAS : | 60607-34-3| Matching products |
| KEGG ID : | K00461 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P330, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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