O-Arachidonoyl Glycidol

O-Arachidonoyl Glycidol
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10010547-5 5 mg -

6 - 10 business days*

83.00€
Cay10010547-10 10 mg -

6 - 10 business days*

157.00€
Cay10010547-50 50 mg -

6 - 10 business days*

660.00€
Cay10010547-100 100 mg -

6 - 10 business days*

1,155.00€
 
2-Arachidonoyl glycerol (2-AG) is an endogenous ligand that binds to both central cannabinoid... more
Product information "O-Arachidonoyl Glycidol"
2-Arachidonoyl glycerol (2-AG) is an endogenous ligand that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors and is involved in the regulation of a broad range of neurotransmitter signalling functions with implications in neurodegenerative diseases, pain, cancer, and obesity. Levels of this endocannabinoid are regulated by hydrolysis to glycerol and arachidonic acid by the enzyme monoacylglycerol lipase. O-Arachidonoyl glycidol is a 2-arachidonoyl glycerol analog that blocks 2-oleoyl glycerol hydrolysis in the cytosolic and membrane fractions of rat cerebella with IC50 values of 4.5 and 19 µM, respectively. O-Arachidonoyl glycidol inhibits fatty acid amide hydrolase-catalyzed hydrolysis of arachidonoyl ethanolamide in the membrane fraction of rat cerebella with an IC50 value of 12 µM. Formal Name: 5Z,8Z,11Z,14Z-eicosatetraenoic acid, oxiranylmethyl ester. CAS Number: 439146-24-4. Molecular Formula: C23H36O3. Formula Weight: 360.5. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 50 mg/ml. SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OCC1CO1. InChi Code: InChI=1S/C23H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(24)26-21-22-20-25-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-. InChi Key: ACYNJBAUKQMZDF-DOFZRALJSA-N.
Keywords: 5Z,8Z,11Z,14Z-eicosatetraenoic acid, oxiranylmethyl ester
Supplier: Cayman Chemical
Supplier-Nr: 10010547

Properties

Application: Fatty acid amide hydrolase inhibitor
MW: 360.5 D
Formula: C23H36O3
Purity: >98%
Format: Solution

Database Information

CAS : 439146-24-4| Find alternatives
KEGG ID : K15528 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H336
P Phrases: P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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