- Search results for K15528
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48 products were found matching "K15528"!
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Item number: Cay10010183-100
Fatty acid amide hydrolase (FAAH) is a serine hydrolase with a major role in the hydrolysis of endocannabinoids. It is composed of an N-terminal transmembrane domain, a catalytic domain containing an amidase signature sequence, a polyproline sequence, and a monotopic membrane binding domain. FAAH is localized to...
Keywords: | FAAH, FAAH1, Oleamide hydrolase 1, Oleamide hydrolase 1, Anandamide amidohydrolase 1, Anandamide amidohydrolase 1,... |
Application: | Enzyme activity |
MW: | 67,5 kD |
716.00€
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Item number: ELK-ELK7632.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human FAAH. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human FAAH. Next,...
Keywords: | FAAH, FAAH1, Oleamide hydrolase 1, Fatty acid ester hydrolase, Anandamide amidohydrolase 1, Fatty-acid amide hydrolase 1 |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: Cay10046-10
URB597 is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH), the enzyme that hydrolyzes anandamide (AEA, Cay-90050) and other simple esters and amides with long unsaturated acyl chains (IC50 = 4.6 nM and 0.5 nM in brain membranes and intact neurons, respectively). URB597 exhibits both...
Keywords: | (3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl)-cyclohexylcarbamate |
Application: | FAAH inhibitor |
CAS | 546141-08-6 |
MW: | 338.4 D |
From 54.00€
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Item number: Cay101600-1
Fatty acid amide hydrolase (FAAH) is a serine hydrolase with a major role in the hydrolysis of endocannabinoids. It is composed of an N-terminal transmembrane domain, a catalytic domain containing an amidase signature sequence, a polyproline sequence, and a monotopic membrane binding domain. FAAH is localized to...
Keywords: | Anti-Faah, Anti-Faah1, Anti-Anandamide amidase, Anti-Anandamide amidase, Anti-Oleamide hydrolase 1, Anti-Oleamide... |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human, rat, mouse, ferret |
422.00€
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Item number: Cay70665-10
Arachidonoyl serotonin is an inhibitor of fatty acid amide hydrolase (FAAH), the enzyme responsible for inactivation of anandamide and other endogenous cannabinoids. It inhibits the FAAH activity isolated from mouse neuroblastoma cells with an IC50 value of 12 µM. Both the Km and the Vmax of the enzyme are affected,...
Keywords: | AA-5HT, N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | FAAH inhibitor |
CAS | 187947-37-1 |
MW: | 462.7 D |
From 66.00€
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Item number: Cay10005196-96
Cayman's FAAH Inhibitor Screening Assay Kit provides a convenient fluorescence-based method for screening FAAH inhibitors. FAAH hydrolyzes AMC arachidonoyl amide resulting in the release of the fluorescent product, 7-amino-4-methylcoumarin (AMC). The fluorophore can be easily analyzed using an excitation wavelength...
Keywords: | Anandamide Amidohydrolase, FAAH, Oleamide Hydrolase |
Application: | FAAH inhibitor screening |
Species reactivity: | human |
436.00€
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Item number: Cay13279-1
Fatty acid amide hydrolase (FAAH) degrades N-acyl ethanolamines (NAEs), including the endocannabinoid arachidonoyl ethanolamide (AEA). PF-3845 is a potent, selective, and irreversible inhibitor of FAAH (Ki = 0.23 µM). It covalently binds FAAH on Ser241 at the catalytic site, resulting in prolonged elevation of AEA...
Keywords: | N-3-pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide |
Application: | FAAH inhibitor |
CAS | 1196109-52-0 |
MW: | 456.5 D |
From 39.00€
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Item number: Cay10674-10
URB937 is a potent fatty acid amide hydrolase (FAAH) inhibitor (IC50 = 26.8 nM, in vitro) that does not penetrate the blood-brain barrier, thus preventing arachidonoyl ethanolamide (AEA, Cay-90050) deactivation only in peripheral tissues. Its ED50 value for FAAH inhibition in brain is 200-fold higher than the ED50...
Keywords: | N-cyclohexyl-carbamic acid, 3'-(aminocarbonyl)-6-hydroxy[1,1'-biphenyl]-3-yl ester |
Application: | FAAH inhibitor |
CAS | 1357160-72-5 |
MW: | 354.4 D |
From 54.00€
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Item number: Cay10010908-5
Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. PF-750 is a potent, time-dependent, irreversible FAAH inhibitor with IC50 values of 0.6 and 0.016 µM when preincubated with recombinant human FAAH for 5 and 60 minutes,...
Keywords: | N-phenyl-4-(quinolin-2-ylmethyl)piperidine-1-carboxamide |
Application: | FAAH inhibitor |
CAS | 959151-50-9 |
MW: | 345.4 D |
From 24.00€
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Item number: Cay19306-25
PF-04457845 is an orally active, irreversible inhibitor of fatty acid amide hydrolase (FAAH, IC50 = 7.2 nM) that is selective against other serine hydrolases. It is a covalent inhibitor that carbamylates the active site serine nucleophile of FAAH. In a rat model of inflammatory pain, oral administration of 0.1 mg/kg...
Keywords: | N-3-pyridazinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methylene]-1-piperidinecarboxamide |
Application: | Irreversible FAAH inhibitor |
CAS | 1020315-31-4 |
MW: | 455.4 D |
From 92.00€
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Item number: Cay23157-5
BIA 10-2474 is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 = 4.9 nM in HEK293T cells expressing the human recombinant enzyme). It also inhibits FAAH2, alpha/beta-hydrolase domain-containing protein 6 (ABHD6), carboxylesterase 2 (CES2), and patatin-like phospholipase domain 6 (PNPLA6) with IC50 values of...
Keywords: | N-cyclohexyl-N-methyl-4-(1-oxido-3-pyridinyl)-1H-imidazole-1-carboxamide |
Application: | FAAH inhibitor |
CAS | 1233855-46-3 |
MW: | 300.4 D |
From 131.00€
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Item number: Cay13140-100
Fatty acid amide hydrolase (FAAH) is the primary enzyme responsible for the hydrolysis of the endocannabinoid arachidonoyl ethanolamide (AEA). 4-(n-Nonyl) benzeneboronic acid is a potent inhibitor of FAAH, with an IC50 of 9.1 nM. It is also able to inhibit monoacylglycerol lipase (MAGL), which hydrolyzes...
Keywords: | B-(4-nonylphenyl)-boronic acid |
Application: | FAAH inhibitor |
CAS | 256383-45-6 |
MW: | 248.2 D |
From 26.00€
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