NX-5948

Item number	Size	Manual	Delivery time	Price
Cay43484-1	1 mg	-	6 - 10 business days*	60.00€
Cay43484-5	5 mg	-	6 - 10 business days*	282.00€
Cay43484-10	10 mg	-	6 - 10 business days*	415.00€
Cay43484-25	25 mg	-	6 - 10 business days*	741.00€

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NX-5948 is a proteolysis-targeting chimera (PROTAC) that drives the degradation of Bruton's... more

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Product information "NX-5948"

NX-5948 is a proteolysis-targeting chimera (PROTAC) that drives the degradation of Bruton's tyrosine kinase (BTK). SMILES NC(C1=C(N=C(N2C[C@H](N3C(N(CC3)C)=O)CCC2)C=N1)NC4=CC=C(C5CCN(CC5)CC6CCN(C7=CN=C(C=C7)C(N[C@H]8CCC(NC8=O)=O)=O)CC6)C=C4)=O InChi Code InChI=1S/C42H54N12O5/c1-50-21-22-54(42(50)59)32-3-2-16-53(26-32)35-24-45-37(38(43)56)39(48-35)46-30-6-4-28(5-7-30)29-14-17-51(18-15-29)25-27-12-19-52(20-13-27)31-8-9-33(44-23-31)40(57)47-34-10-11-36(55)49-41(34)58/h4-9,23-24,27,29,32,34H,2-3,10-22,25-26H2,1H3,(H2,43,56)(H,46,48)(H,47,57)(H,49,55,58)/t32-,34+/m1/s1 InChi Key HPTPDBYCFHFWJG-CWTKIQHKSA-N

Keywords:	3-[[4-[1-[[1-[6-[[[(3S)-2,6-dioxo-3-piperidinyl]amino]carbonyl]-3-pyridinyl]-4-piperidinyl]methyl]-4-piperidinyl]phenyl]amino]-5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]-2-pyrazinecarboxamide
Supplier:	Cayman Chemical
Supplier-Nr:	43484

Properties

Application:	BTK degradation driving PROTAC
MW:	806.97 D
Formula:	C42H54N12O5
Purity:	>98%
Format:	Crystalline Solid

Database Information

CAS :	2649400-34-8\| Matching products
KEGG ID :	K07370 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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