NV03 | CAS 2448341-58-8 | Cayman Chemical

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Item number	Size	Manual	Delivery time	Price
Cay45383-1	1 mg	-	6 - 10 business days*	139.00€
Cay45383-5	5 mg	-	6 - 10 business days*	585.00€
Cay45383-10	10 mg	-	6 - 10 business days*	1,101.00€

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NV03 is an inhibitor of the protein-protein interaction between E3 ubiquitin-protein ligase UHRF1... more

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Product information "NV03"

NV03 is an inhibitor of the protein-protein interaction between E3 ubiquitin-protein ligase UHRF1 (UHRF1) and histone H3 trimethylated lysine 9 (H3K9Me3). It binds the tandem Tudor domain (TTD) of UHRF1 (Kd = 2.4 µM) and is selective for the UHRF1-TTD over a panel of 36 demethylases at 10 µM.. SMILES: CC1=C2N(C3=C1SC=C3)C(C)=NN(C2=O)CC(NCCCN(CC)CC)=O. InChi Code: InChI=1S/C19H27N5O2S/c1-5-22(6-2)10-7-9-20-16(25)12-23-19(26)17-13(3)18-15(8-11-27-18)24(17)14(4)21-23/h8,11H,5-7,9-10,12H2,1-4H3,(H,20,25). InChi Key: KNZQAVKYBBYDKV-UHFFFAOYSA-N

Keywords:	N-[3-(diethylamino)propyl]-5,9-dimethyl-8-oxo-thieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazine-7(8H)-acetamide
Supplier:	Cayman Chemical
Supplier-Nr:	45383

Properties

Application:	UHRF1-H3K9Me3 protein-protein interaction inhibitor
MW:	389.52 D
Formula:	C19H27N5O2S
Purity:	>98%
Format:	Solid

Database Information

CAS :	2448341-58-8\| Matching products
KEGG ID :	K10638 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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