Nonyloxytryptamine (oxalate)

Nonyloxytryptamine is a potent agonist of the serotonin (5-HT) receptor 5-HT1Dbeta with an EC50 value of 68 nM for adenylate cyclase activity in CHOKM6 cells transfected with the human 5-HT1Dbeta receptor. It is selective for 5-HT1Dbeta over 5-HT1A for its adenylate cyclase activity, with an EC50 greater than 1 µM for 5-HT1A. It binds to 5-HT1Dbeta, 5-HT1A, 5-HT1B, 5-HT2A, and 5-HT2C receptors in vitro (Kis = 1.2-315 nM). Nonyloxytryptamine also inhibits reovirus-mediated cell death in a dose-dependent manner but has no effect on reovirus attachment or internalization.Formal Name: 5-(nonyloxy)-1H-indole-3-ethanamine, monoethanedioate. CAS Number: 157798-13-5. Molecular Formula: C19H30N2O . C2H2O4. Formula Weight: 392.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml, DMSO: 20 mg/ml, Ethanol: slightly soluble. lambdamax: 278 nm. SMILES: NCCC1=CNC2=CC=C(OCCCCCCCCC)C=C21.OC(C(O)=O)=O. InChi Code: InChI=1S/C19H30N2O.C2H2O4/c1-2-3-4-5-6-7-8-13-22-17-9-10-19-18(14-17)16(11-12-20)15-21-19,3-1(4)2(5)6/h9-10,14-15,21H,2-8,11-13,20H2,1H3,(H,3,4)(H,5,6). InChi Key: JORSCLBFSAAOFR-UHFFFAOYSA-N.