148 products were found matching "K04153"!

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NAS-181
NAS-181

Item number: Cay39191-1

NAS-181 is an antagonist of the serotonin (5-HT) receptor subtype 5-HT1B (Ki = 47 nM for the rat receptor). It is selective for 5-HT1B over 5-HT1A, 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 (Kis = >3,000 nM for all for the rat receptors). NAS-181 (100 or 1,000 nM) potentiates potassium-stimulated 5-HT release in isolated and...
Keywords: (2R)-2-[[[3-(4-morpholinylmethyl)-2H-1-benzopyran-8-yl]oxy]methyl]-morpholine, bimethanesulfonate
Application: 5-HT1B receptor antagonist
CAS 1217474-40-2
MW: 538.6 D
From 74.00€ *
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Ipsapirone
Ipsapirone

Item number: Cay39918-10

Ipsapirone is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A (Ki = 10 nM in hippocampal membranes). It reduces 5-HT release in the rat ventral hippocampus in vivo. Low doses of ipsapirone decrease, while high doses increase, extracellular dopamine release in the murine nucleus accumbens....
Keywords: 2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3(2H)-one, 1,1-dioxide
Application: 5-HT1A receptor partial agonist
CAS 95847-70-4
MW: 401.5 D
From 106.00€ *
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Human 5HTR1A (5-Hydroxytryptamine Receptor 1A) ELISA Kit
Human 5HTR1A (5-Hydroxytryptamine Receptor 1A) ELISA Kit

Item number: ELK-ELK4282.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human 5HTR1A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human 5HTR1A....
Keywords: G-21, HTR1A, 5-HT1A, 5-HT-1A, ADRB2RL1, Serotonin receptor 1A, 5-hydroxytryptamine receptor 1A
Application: ELISA
Species reactivity: human
365.00€ * From 328.50€ *
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Mouse 5HTR1A (5-Hydroxytryptamine Receptor 1A) ELISA Kit
Mouse 5HTR1A (5-Hydroxytryptamine Receptor 1A) ELISA Kit

Item number: ELK-ELK8645.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse 5HTR1A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse 5HTR1A....
Keywords: Htr1a, 5-HT1A, Gpcr18, 5-HT-1A, Serotonin receptor 1A, 5-hydroxytryptamine receptor 1A
Application: ELISA
Species reactivity: mouse
365.00€ * From 328.50€ *
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Serotonin (hydrochloride)
Serotonin (hydrochloride)

Item number: Cay14332-50

Serotonin is a monoamine neurotransmitter that is biochemically derived from tryptophan and produced in serotonergic neurons in the central nervous system and in enterochromaffin cells in the gastrointestinal tract. Serotonin is important in the regulation of mood, sleep, vomiting, sexuality, and appetite. Low...
Keywords: 5-HT, 5-Hydroxytryptamine, 3-(2-aminoethyl)-1H-indol-5-ol, monohydrochloride
Application: Monoamine neurotransmitter
CAS 153-98-0
MW: 212.7 D
From 50.00€ *
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2-bromo LSD (solution)
2-bromo LSD (solution)

Item number: Cay36791-100

2-bromo LSD (solution) (Cay-36791) is an analytical reference material categorized as a lysergamide. Unlike LSD (Cay-28289), 2-bromo LSD does not induce myoclonic jumping activity in guinea pigs, indicating a lack of hallucinogenic potential. This product is intended for research and forensic applications.Formal...
Keywords: BOL-148, Bromolysergic Acid diethylamide, Bromolysergide,...
Application: Analytical reference material, Lysergamide, Neutral antagonist
CAS 478-84-2
MW: 402.3 D
158.00€ *
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Buspirone (hydrochloride)
Buspirone (hydrochloride)

Item number: Cay22028-1

Buspirone (hydrochloride) (Cay-22028) is an analytical reference standard that is categorized as an anxiolytic. It modulates serotonin and dopamine receptors, undergoes rapid first-pass metabolism, and is metabolized to phenylpiperazine (Cay-11203), which has high affinity for alpha-adrenergic receptors. This...
Keywords: MJ9022-1, 8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione, monohydrochloride
Application: Analytical reference standard, Anxiolytic, Serotonin 5-HT1A receptor agonist
CAS 33386-08-2
MW: 422 D
From 77.00€ *
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Brexpiprazole
Brexpiprazole

Item number: Cay22906-10

Brexpiprazole is a serotonin (5-HT) and dopamine receptor modulator that has high affinity (Ki = 1A and 5-HT2A serotonin, dopamine D2L, and alpha1B-, and alpha2C-adrenergic receptors in CHO cell membranes expressing the human receptors. It acts as a partial agonist of 5-HT1A, D2L, and D3 receptors (EC50s = 0.49,...
Keywords: OPC 34712, 7-[4-(4-benzo[b]thien-4-yl-1-piperazinyl)butoxy]-2(1H)-quinolinone
Application: 5-HT1A-receptor agonist
CAS 913611-97-9
MW: 433.6 D
From 60.00€ *
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Dihydroergotamine (mesylate)
Dihydroergotamine (mesylate)

Item number: Cay23847-25

Dihydroergotamine is a derivative of ergotamine and an agonist of the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D (Kis = 0.3 and 2.5 nM, respectively, for human receptors). It binds to dopamine D2 and D3 as well as 5-HT2A receptors (K0.5s = 5, 16, and 38 nM, respectively) but has lower affinity for D1,...
Keywords: (+)-Dihydroergotamine, (5'alpha,10alpha)-9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-ergotaman-3',6',18-trione,...
Application: alpha1-Adrenergic receptor & serotonin receptor agonist/antagonist, dopamine D2 receptor agonist
CAS 6190-39-2
MW: 679.8 D
From 50.00€ *
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Flibanserin
Flibanserin

Item number: LKT-F4532.100

Flibanserin is an agonist at 5-HT1A receptors and an antagonist at 5-HT2A receptors. Flibanserin is clinically used to treat hypoactive sexual disorder in females. Flibanserin also decreases dystonia induced by L-DOPA and quinelorane in animal models of Parkinson's disease.
Application: 5-HT1A-receptor agonist, 5-HT2-receptor antagonist
CAS 167933-07-5
MW: 390.4 D
From 104.00€ *
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WAY-100635 (maleate)
WAY-100635 (maleate)

Item number: Cay14599-5

WAY-100635 is a potent, silent antagonist of serotonin 5-HT1A receptors with an IC50 value of 2.2 nM (Ki = 0.8 nM) for inhibiting 5-HT1A receptors in rat hippocampal membranes. Because it displays 100-fold selectivity for 5-HT1A over other 5-HT subtypes, WAY-100635 is classically used to examine the distribution and...
Keywords: N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-cyclohexanecarboxamide, 2Z-butenedioate
Application: 5-HT1A receptor antagonist
CAS 1092679-51-0
MW: 538.6 D
From 109.00€ *
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Methiothepin (maleate)
Methiothepin (maleate)

Item number: Cay23138-50

Methiothepin is a non-selective antagonist of the serotonin (5-HT) receptor. It is a potent antagonist of 5-HT1A and 5-HT1B (IC50 = 16 nM and Ki = 0.2 nM, respectively) as well as 5-HT2A, 5-HT2B, and 5-HT2C receptors (Kis = 3.16, 2.08, and 4.46 nM, respectively). Methiothepin binds to 5-HT5A, 5-HT5B, 5-HT6, and...
Keywords: Metitepine, 1-[10,11-dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methyl-piperazine, (2Z)-butenedioate
Application: 5-HT2 / 5-HT1 antagonist
CAS 19728-88-2
MW: 472.6 D
From 43.00€ *
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