Nintedanib esylate
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor... more
Product information "Nintedanib esylate"
Description: Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor targeting VEGFR1/2/3, FGFR1/2/3, and PDGFRalpha/beta. Target: PDGFR, FGFR, VEGFR. Smiles: CCS(O)(=O)=O.COC(=O)c1ccc2c(NC(=O)\C2=C(/Nc2ccc(cc2)N(C)C(=O)CN2CCN(C)CC2)c2ccccc2)c1. References: Roth GJ, et al. Design, synthesis, and evaluation of indolinones as triple angiokinase inhibitors and the discovery of a highly specific 6-methoxycarbonyl-substituted indolinone (BIBF 1120). J Med Chem, 2009, 52(14), 4466-4480.
| Keywords: | BIBF 1120 (esylate), Intedanib, Nintedanib Ethanesulfonate Salt, BIBF 1120 |
| Supplier: | TargetMol |
| Supplier-Nr: | T5001 |
Properties
| Application: | Targets FMS-like tyrosine kinase 1 [EC:2.7.10.1] (FLT1, VEGFR1) |
| MW: | 649.76 D |
| Formula: | C31H33N5O4.C2H6O3S |
Database Information
| CAS : | 656247-18-6| Matching products |
| KEGG ID : | K04362 | Matching products |
| Protein Atlas Nr. : | Tyrosine Phosphorylation |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H360 |
| P Phrases: | P201, P202, P280, P308+313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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