Nilotinib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor with oral activity.... more
Product information "Nilotinib"
Description: Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor with oral activity. Nilotinib has antitumor activity and may be used for the treatment of Imatinib-resistant chronic myelogenous leukemia (CML). Target: Bcr-Abl, Autophagy. Smiles: C(F)(F)(F)C=1C=C(C=C(NC(=O)C2=CC(NC=3N=C(C=CN3)C=4C=CC=NC4)=C(C)C=C2)C1)N5C=NC(C)=C5. References: O'Hare T, et al. In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants. Cancer Res. 2005 Jun 1,65(11):4500-5.
| Keywords: | AMN107, Tasigna |
| Supplier: | TargetMol |
| Supplier-Nr: | T1524 |
Properties
| Application: | Targets abelson tyrosine-protein kinase 1 [EC:2.7.10.2] (ABL1) |
| MW: | 529.52 D |
| Formula: | C28H22F3N7O |
Database Information
| CAS : | 641571-10-0| Matching products |
| KEGG ID : | K05091 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H372, H413 |
| P Phrases: | P260, P264, P270, P273, P314, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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