501 products were found matching "K05091"!

Recombinant human CD117, also known as c-Kit, encompassing amino acids 26-520, corresponding to the extracellular domain of the protein. This construct contains a C-terminal His-tag (6xHis). The protein was affinity purified. c-KIT is a proto-oncogene and a type III transmembrane receptor for mast cell growth...

Briquilimab, also known as JSP-191 or AMG-191, is a humanized IgG1 monoclonal antibody that targets CD117 (or c-Kit). Briquilimab blocks the interaction between CD117 receptor and stem cell factor. c-KIT is a proto-oncogene and a type III transmembrane receptor for mast cell growth factor, also known as stem cell...

Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF...

In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. The Kit protein in zebrafish (Danio rerio), encoded by the kit gene (also referred to as kita or kitb depending on isoform), is a homolog of the mammalian c-Kit receptor, a type III receptor tyrosine kinase. Kit plays an essential role in multiple developmental...

Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In...

CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells...

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with...

Immunogen: Erythroleukemia cell line OCIM1  Host: Mouse  Species Reactivity: (+) Human  Cross Reactivity: (+) c-Kit  Applications: FC. Formulation: 100 µg of protein G-purified monoclonal antibody. InChI: . InChIKey: . SMILES:

Active human Kit Kit (V654A) ( GenBank Accession No. NM_000222), (a.a. 544- 976) with N-terminal His tag, MW=53.4 kDa, expressed in an Baculovirus infected Sf9 cell expression system.

Human CD117 (c-kit) is a transmembrane protein with receptor tyrosine kinase capacity and serves as the receptor for steel factor (SLF). CD117 is expressed on almost all hematopoietic progenitor cells and receptor/ligand interaction is crucial for development of hematopoietic stem cells.

BLU-285 is a dual inhibitor of KIT receptor and platelet-derived growth factor receptor alpha (PDGFRalpha) tyrosine kinases with activating loop mutations (IC50s = 0.27 and 0.24 nM for KITD816V and PDGFRalphaD842V, respectively). It is >150-fold selective for KITD816V and PDGFRalphaD842V over a kinase panel at a...