Naratriptan hydrochloride
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a... more
Product information "Naratriptan hydrochloride"
Description: Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride (GR-85548A hydrochloride) binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides. Target: 5-HT Receptor. Smiles: Cl.CNS(=O)(=O)CCc1ccc2[nH]cc(C3CCN(C)CC3)c2c1. References: Sattar M, Hadgraft J, Lane ME.Int J Pharm. 2015 Sep 30,493(1-2):146-51.
| Keywords: | Naratriptan HCl, GR-85548A hydrochloride, Amerge, Naramig |
| Supplier: | TargetMol |
| Supplier-Nr: | T6602 |
Properties
| Application: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| MW: | 371.93 D |
| Formula: | C17H25N3O2S·HCl |
Database Information
| CAS : | 143388-64-1| Matching products |
| KEGG ID : | K04153 | Matching products |
| Protein Atlas Nr. : | GPCR Modulators/A(nta)gonists |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H319 |
| P Phrases: | P264, P280, P305+351+338, P337+313 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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