N,N-Dipropyldopamine (hydrobromide)

Description: N,N-Dipropyldopamine is a dopamine receptor agonist.1,2,3 It decreases dihydrophenylalanine (DOPA) levels in the limbic forebrain and striatum of reserpinized rats (ED50s = 25 and 20 µmol/kg, respectively), as well as reduces homovanillic acid levels in rat striatum when administered at a dose of 80 µmol/kg.1 N,N-Dipropyldopamine (0.5-16 mg/kg) reduces spontaneous locomotor activity in mice, an effect that can be reversed by the antipsychotic spiroperidol.2,3. Target: Others. Smiles: Br.CCCN(CCC)CCc1ccc(O)c(O)c1. References: Wikstr?m, H., Lindberg, P., Martinson, P., et al. Pivaloyl esters of N,N-dialkylated dopamine congeners. Central dopamine-receptor stimulating activity. J. Med. Chem. 21(9), 864-867 (1978).