MSD-M1PAM

MSD-M1PAM
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay41358-500 500 µg - -

5 - 10 business days*

80.00€
Cay41358-1 1 mg - -

5 - 10 business days*

143.00€
 
A positive allosteric modulator of M1 mAChRs, enhances ACh-induced calcium production in a... more
Product information "MSD-M1PAM"
A positive allosteric modulator of M1 mAChRs, enhances ACh-induced calcium production in a calcium mobilization assay from 0.1-10 µM, reverses scopolamine-induced deficits in freezing behavior in mice from 1-30 mg/kg, attenuates deficits in self-ordered spatial search in cynomolgus macaques and in the object retrieval detour task in rhesus macaques. Formulation: A solid. InChI: InChI=1S/C22H20N4O3/c23-15-22(19-6-1-3-9-24-19)7-11-25(12-8-22)14-16-13-17(21(28)29)20(27)26-10-4-2-5-18(16)26/h1-6,9-10,13H,7-8,11-12,14H2,(H,28,29). InChIKey: RJTJRVASUFIDQM-UHFFFAOYSA-N. SMILES: O=C(O)C1=CC(CN2CCC(C3=NC=CC=C3)(C#N)CC2)=C4C=CC=CN4C1=O
Keywords: PQCA, 1-[[4-cyano-4-(2-pyridinyl)-1-piperidinyl]methyl]-4-oxo-4H-quinolizine-3-carboxylic acid
Supplier: Cayman Chemical
Supplier-Nr: 41358

Properties

Application: Muscarinic acetylcholine receptor M1 positive allosteric modulator
Immunogen: 388.4
MW: 388.4 D
Formula: C22H20N4O3
Purity: >98%
Format: Solid

Database Information

CAS : 1144504-35-7| Matching products
KEGG ID : K04129 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
P Phrases: P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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