MMV390048

NEW

Item number	Size	Delivery time	Price
TGM-T16125-5mg	5 mg	5 - 10 business days*	46.00€
TGM-T16125-1mL	1 ml	5 - 10 business days*	50.00€
TGM-T16125-10mg	10 mg	5 - 10 business days*	70.00€
TGM-T16125-25mg	25 mg	5 - 10 business days*	139.00€
TGM-T16125-50mg	50 mg	5 - 10 business days*	224.00€
TGM-T16125-100mg	100 mg	5 - 10 business days*	346.00€

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Description: MMV390048 is an antimalarial agent and is a representative of a new chemical class... more

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Product information "MMV390048"

Description: MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 µM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns. Target: PI4K, Parasite. Smiles: CS(=O)(=O)c1ccc(cc1)-c1cnc(N)c(c1)-c1ccc(nc1)C(F)(F)F. References: Paquet T, et al. Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase. Sci Transl Med. 2017 Apr 26,9(387). pii: eaad9735.

Supplier:	TargetMol
Supplier-Nr:	T16125

Properties

MW:	393.38 D
Formula:	C18H14F3N3O2S

Database Information

CAS :

1314883-11-8| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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