MMV390048
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Larger quantity required? Request bulk
A P. vivax PI4K inhibitor (IC50 = 3.4 nM), active against P. falciparum (IC50 = 28 nM), decreases... more
Product information "MMV390048"
A P. vivax PI4K inhibitor (IC50 = 3.4 nM), active against P. falciparum (IC50 = 28 nM), decreases the blood levels of P. falciparum in P. falciparum-infected mice (ED90 = 0.57 mg/kg), reduces the hepatic levels of hypnozoite- and schizont-stage P. cynomolgi parasites in P. cynomolgi-infected rhesus monkeys at 20 mg/kg per day. Formulation: A solid. InChI: InChI=1S/C18H14F3N3O2S/c1-27(25,26)14-5-2-11(3-6-14)13-8-15(17(22)24-10-13)12-4-7-16(23-9-12)18(19,20)21/h2-10H,1H3,(H2,22,24). InChIKey: RTJQABCNNLMCJF-UHFFFAOYSA-N. SMILES: O=S(C1=CC=C(C2=CN=C(C(C3=CN=C(C(F)(F)F)C=C3)=C2)N)C=C1)(C)=O
| Keywords: | 5-[4-(methylsulfonyl)phenyl]-6'-(trifluoromethyl)-[3,3'-bipyridin]-2-amine |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 41835 |
Properties
| Application: | Plasmodium vivax PI4K inhibitor |
| Immunogen: | 393.4 |
| MW: | 393.4 D |
| Formula: | C18H14F3N3O2S |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 1314883-11-8| Matching products |
| KEGG ID : | K00888 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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