ML-218
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
ML-218 is an inhibitor of T-type voltage-gated calcium channel 3.2 (Cav3.2) and Cav3.3. It... more
Product information "ML-218"
ML-218 is an inhibitor of T-type voltage-gated calcium channel 3.2 (Cav3.2) and Cav3.3. It inhibits currents in whole-cell patch clamp assays using HEK293 cells expressing Cav3.2 or Cav3.3 (IC50s = 310 and 274 nM, respectively). ML-218 (0.1-30 mg/kg) decreases the latency to paw withdrawal in a rat model of catalepsy induced by haloperidol (Cay12014). SMILES [H][C@]12CN(C[C@@]([C@@H]2CNC(C3=CC(Cl)=CC(Cl)=C3)=O)1[H])CCC(C)(C)C InChi Code InChI=1S/C19H26Cl2N2O/c1-19(2,3)4-5-23-10-16-15(17(16)11-23)9-22-18(24)12-6-13(20)8-14(21)7-12/h6-8,15-17H,4-5,9-11H2,1-3H3,(H,22,24)/t15-,16-,17+ InChi Key GSJIGYLGKSBYBC-OSYLJGHBSA-N
| Keywords: | 3,5-dichloro-N-[[(1alpha,5alpha,6alpha)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]methyl]-benzamide |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 43541 |
Properties
| Application: | Cav3.2 / Cav3.3 inhibitor |
| MW: | 369.33 D |
| Formula: | C19H26Cl2N2O |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 1346233-68-8| Matching products |
| KEGG ID : | K04856 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H319, H413 |
| P Phrases: | P264, P273, P280, P305+351+338, P337+313, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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