Midostaurin
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: PKC412(Midostaurin (PKC412), CGP41231, CGP41251) is a broad spectrum protein kinase... more
Product information "Midostaurin"
Description: PKC412(Midostaurin (PKC412), CGP41231, CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3) tyrosine kinases, which may result in disruption of the cell cycle, inhibition of proliferation, apoptosis, and inhibition of angiogenesis in susceptible tumors. Target: Others, PKC. Smiles: COC1C(CC2OC1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1. References: Fabbro D, et al. Pharmacol Ther, 1999, 82(2-3), 293-301.
| Keywords: | CGP41231, CGP 41251, N-Benzoylstaurosporine, PKC412 |
| Supplier: | TargetMol |
| Supplier-Nr: | T3211 |
Properties
| Application: | Targets fms-related tyrosine kinase 3 [EC:2.7.10.1] (FLT3, FLK2, CD135) |
| MW: | 570.64 D |
| Formula: | C35H30N4O4 |
Database Information
| CAS : | 120685-11-2| Matching products |
| KEGG ID : | K02677 | Matching products |
| Protein Atlas Nr. : | Ser/Thr Phosphorylation |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H361, H373, H410 |
| P Phrases: | P201, P202, P260, P264, P270, P273, P280, P314, P330, P391, P301+P310, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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