(±)-Mesembrenol

(±)-Mesembrenol
NEW
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay40470-500 500 µg -

6 - 10 business days*

551.00€
Cay40470-1 1 mg -

6 - 10 business days*

1,045.00€
 
(±)-Mesembrenol is an alkaloid that has been found in S. tortuosum and has diverse biological... more
Product information "(±)-Mesembrenol"
(±)-Mesembrenol is an alkaloid that has been found in S. tortuosum and has diverse biological activities. It binds to the serotonin transporter (SERT) with a Ki value of 62 nM. (±)-Mesembrenol reduces single-shock- and theta burst-stimulated population spike amplitudes in rat hippocampal slices. It also reduces population spike amplitudes increased by the AMPA agonist (S)-(-)-5-fluorowillardiine (Cay37372) when used at a concentration of 0.035 µM. (±)-Mesembrenol (10-50 µM) reduces anxiety-like behavior in zebrafish larvae in a light-dark challenge. As one of the major mesembrine-type alkaloids found in certain chemotypes of S. tortuosum, (±)-mesembrenol can be used as a marker compound in the quality control of S. tortuosum raw materials and finished products.. SMILES: COC1=C(OC)C=C(C2(CCN3C)C3([H])C[C@H](O)C=C2)C=C1. InChi Code: InChI=1S/C17H23NO3/c1-18-9-8-17(7-6-13(19)11-16(17)18)12-4-5-14(20-2)15(10-12)21-3/h4-7,10,13,16,19H,8-9,11H2,1-3H3/t13-,16?,17?/m1/s1. InChi Key: PQBHZMSTECYZLH-NVPAJSRCSA-N
Keywords: (6S)-3a-(3,4-dimethoxyphenyl)-1-methyl-2,3,3a,6,7,7a-hexahydro-1H-indol-6-ol
Supplier: Cayman Chemical
Supplier-Nr: 40470

Properties

Application: Bioactive, serotonin transporter (SERT) binding alkaloid
MW: 289.37 D
Formula: C17H23NO3
Purity: >98%
Format: Solution

Database Information

KEGG ID : K05037 | Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319
P Phrases: P210, P233, P240, P241, P242, P243, P264, P280, P303+361+353, P305+351+338, P337+313, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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