Magnolol

Magnolol is a bioactive compound isolated from the bark of M. officinalis that has been used in Asian traditional medicine for the treatment of anxiety, sleep disorders, and allergic diseases. Magnolol can activate cannabinoid (CB) receptors, behaving as a partial agonist with selectivity for the peripheral CB2 subtype (EC50 = 3.28 µM, Ki = 1.44 µM) versus central CB1 (EC50 = 18.3 µM, Ki = 3.15 µM).Formal Name: 5,5'-di-2-propen-1-yl-[1,1'-biphenyl]-2,2'-diol. CAS Number: 528-43-8. Synonyms: NSC 293099. Molecular Formula: C18H18O2. Formula Weight: 266.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 16 mg/ml, Ethanol: 20 mg/ml, Ethanol:PBS(pH 7.2) (1:5): 0.16 mg/ml. lambdamax: 215, 292 nm. SMILES: OC(C=CC(CC=C)=C1)=C1C2=CC(CC=C)=CC=C2O. InChi Code: InChI=1S/C18H18O2/c1-3-5-13-7-9-17(19)15(11-13)16-12-14(6-4-2)8-10-18(16)20/h3-4,7-12,19-20H,1-2,5-6H2. InChi Key: VVOAZFWZEDHOOU-UHFFFAOYSA-N.