LN6023 (hydrochloride)

LN6023 is an agonist of chemokine (C-X-C motif) receptor 7 (CXCR7). It induces beta-arrestin recruitment in a reporter assay using HEK293T cells expressing human CXCR7 (EC50 = 3.5 µM) but not in HEK293T cells expressing human CXCR4. LN6023 (100 µM) reduces surface levels of P-selectin in isolated and washed human platelets.Formal Name: N-(tert-butyl)-1-(3-((7-ethyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)amino)propyl)piperidine-4-carboxamide, dihydrochloride. Molecular Formula: C20H32N6O2S . 2HCl. Formula Weight: 493.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: Slightly Soluble, Water: Soluble. SMILES: O=C1C=C(CC)N=C2N1N=C(NCCCN3CCC(C(NC(C)(C)C)=O)CC3)S2.Cl.Cl. InChi Code: InChI=1S/C20H32N6O2S.2ClH/c1-5-15-13-16(27)26-19(22-15)29-18(24-26)21-9-6-10-25-11-7-14(8-12-25)17(28)23-20(2,3)4,,/h13-14H,5-12H2,1-4H3,(H,21,24)(H,23,28),2*1H. InChi Key: WPTAIRZLERPUIM-UHFFFAOYSA-N.