Lenacapavir

Item number	Size	Manual	SDS	Delivery time	Price
Cay41830-5	5 mg	-	-	5 - 10 business days*	269.00€
Cay41830-10	10 mg	-	-	5 - 10 business days*	483.00€
Cay41830-25	25 mg	-	-	5 - 10 business days*	1,070.00€
Cay41830-50	50 mg	-	-	5 - 10 business days*	1,472.00€

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An inhibitor of HIV capsid protein-protein interactions, inhibits viral replication in... more

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Product information "Lenacapavir"

An inhibitor of HIV capsid protein-protein interactions, inhibits viral replication in HIV-1-infected primary human CD4+ T cells and macrophages (mean IC50s = 32 and 56 pM, respectively), two HIV-2 clinical isolates (mean IC50 = 885 pM), and 23 HIV-1 clinical isolates (mean IC50 = 50 pM), prevents stHIV-A19 infection in pigtail macaques at 25 mg/kg, s.c.. Formulation: A solid. InChI: InChI=1S/C39H32ClF10N7O5S2/c1-36(2,63(3,59)60)10-9-21-5-6-22(23-7-8-26(40)30-32(23)57(17-37(43,44)45)54-35(30)55-64(4,61)62)31(51-21)27(13-18-11-19(41)14-20(42)12-18)52-28(58)16-56-34-29(33(53-56)39(48,49)50)24-15-25(24)38(34,46)47/h5-8,11-12,14,24-25,27H,13,15-17H2,1-4H3,(H,52,58)(H,54,55)/t24-,25+,27-/m0/s1. InChIKey: BRYXUCLEHAUSDY-WEWMWRJBSA-N. SMILES: O=C(N[C@H](C1=C(C(C=C2)=C(N3CC(F)(F)F)C(C(NS(C)(=O)=O)=N3)=C2Cl)C=CC(C#CC(C)(C)S(C)(=O)=O)=N1)CC4=CC(F)=CC(F)=C4)CN5N=C(C(F)(F)F)C6=C5C(F)(F)[C@@]7([H])[C@]6([H])C7

Keywords:	GS-6207, GS-714207, GS-CA2, (3bS,4aR)-N-[(1S)-1-[3-[4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-[3-methyl-3-(methylsulfonyl)-1-butyn-1-yl]-2-pyridinyl]-2-(3,5-difluorophenyl)ethyl]-5,5-difluoro-3b,4,4a,5-tetrahydro-3-(tr
Supplier:	Cayman Chemical
Supplier-Nr:	41830

Properties

Application:	HIV capsid protein-protein interaction inhibitor
Immunogen:	968.28
MW:	968.28 D
Formula:	C39H32ClF10N7O5S2
Purity:	>98%
Format:	Solid

Database Information

CAS :	2189684-44-2\| Matching products
KEGG ID :	K25306 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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