Landiolol (hydrochloride)
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Landiolol is an antagonist of the beta1-adrenergic receptor (beta1-AR). It selectively induces... more
Product information "Landiolol (hydrochloride)"
Landiolol is an antagonist of the beta1-adrenergic receptor (beta1-AR). It selectively induces relaxation of isolated and perfused guinea pig atrial strips that endogenously express beta1-ARs over isolated and perfused guinea pig tracheal strips that endogenously express beta2-ARs (pA2s = 6. and 4. respectively). Infusion of landiolol (10 µg/kg per minute) inhibits tachycardia induced by isoproterenol (Cay-15592) in dogs. Formulations containing landiolol have been used in the treatment of supraventricular tachycardia. InChI: InChI=1S/C25H39N3O8.ClH/c1-25(2)35-18-22(36-25)17-34-23(30)8-5-19-3-6-21(7-4-19)33-16-20(29)15-26-9-10-27-24(31)28-11-13-32-14-12-28,/h3-4,6-7,20,22,26,29H,5,8-18H2,1-2H3,(H,27,31),1H/t20-,22+,/m0./s1, InChIKey: DLPGJHSONYLBKP-IKGOIYPNSA-N, SMILES: CC(C)(OC1)O[C@@H]1COC(CCC2=CC=C(C=C2)OC[C@@H](O)CNCCNC(N3CCOCC3)=O)=O.Cl
| Keywords: | ONO-1101 |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 44229 |
Properties
| Application: | beta1-adrenergic receptor (beta1-AR) antagonis |
| MW: | 546.06 D |
| Formula: | C25H39N3O8 . HCl |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 144481-98-1| Matching products |
| KEGG ID : | K04141 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319 |
| P Phrases: | P264, P280, P302+352, P305+351+338, P321, P332+313, P337+313, P362+364 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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