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Description: L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 µM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively). Target: GluR. Smiles: C([C@@H](C(O)=O)N)CP(=O)(O)O. References: Selvam C, et al. Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites. J Med Chem. 2018 Mar 8,61(5):1969-1989.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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