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L-AP4
L-AP4

Item number: Cay14538-1

Metabotropic glutamate receptors (mGluR) function to modulate excitatory synaptic transmission in the brain. Eight subtypes (1-8) and multiple splice variants of the mGluR have been identified and grouped based on their pharmacological properties. Group I mGluRs (subtypes 1 and 5) activate the phosphatidyl inositol...
Keywords: L-(+)-2-amino-4-phosphorobutanoic acid, L-APB, 2S-amino-4-phosphono-butanoic acid
Application: Group III mGluR agonist
CAS 23052-81-5
MW: 183.1 D
From 107.00€ *
Review
L-AP4
L-AP4

Item number: TGM-T15692-10mg

Description: L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 µM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively). Target: GluR. Smiles: C([C@@H](C(O)=O)N)CP(=O)(O)O. References: Selvam C, et al. Increased Potency and Selectivity for Group III Metabotropic...
Keywords: L-APB, L-AP 4
CAS 23052-81-5
MW: 183.1 D
From 187.00€ *
Review